Exercise and Cellular Senescence

Received: 16 March 2021 | Revised: 22 April 2021 | Accepted: 14 May 2021 DOI: 10.1111/acel.13415SHORT TAKEExercise reduces circulating biomarkers of cellular senescence in humansDavis A. Englund1,2 | Ayumi E. Sakamoto1,2 | Chad M. Fritsche3 |Amanda A. Heeren1,2 | Xu Zhang1 | Brian R. Kotajarvi4 | Denise R. Lecy3 | Matthew J. Yousefzadeh5 | Marissa J. Schafer1,6 | Thomas A. White1,2 |Elizabeth J. Atkinson7 | 1Robert and Arlene Kogod Center onAging, Mayo Clinic, Rochester, MN, Read more…

Age Reduction Breakthrough

Posted on May 11, 2020 In the race to effect substantial, system-wide rejuvenation, Harold Katcher is a dark horse. He has the right academic credentials and a solid history of research. In fact, in earlier life he was part of a team that discovered the breast cancer gene, brca1. I asked Harold for a biographical sketch, and have printed it in a box at the end of this posting. One thing Katcher has going for him is the Read more…

Truth! More elusive than ever before.

Truth has been hard to come by in recent years or maybe I have just been paying more attention recently. Did politicians and reporters always spin the truth? I suppose that they did but the difference now seems to be it is more organized. Like there are meetings and scripts put out to ensure that that spun message stays on point. That the misdirection ensures that the general population gets the message as intended. Any Read more…

Fear

What has fear got to do with it? Are we letting fear dictate are lives? Fear is suppose to be a healthy emotion. Fear is healthy in that it imparts control over your response to dangerous situations. Fear can save us from threats whether physical, emotional or psychological. So when utilize as intended fear is a good thing it can be life saving. But, fear can also be debilitating and we can learn to fear Read more…

Frozen

Covid-19 has frozen my life. When this all started it was two weeks to flatten the curve and then life would return to normal. While almost a year later that two weeks never really ended. We are still battling the unseen enemy and my life probably like yours resembles nothing like it did. In February 2020 I ran my first Spartan Race of the year in Arizona. I had a whole slate of races planned Read more…

What to do and When to do it?

Life moves fast and there are many head fakes along the way. We get so caught up in the business of day to day life we don’t have the bandwidth to look at what is really important. We struggle everyday and forget to enjoy the little things in life. Then there is the end goal, retirement where life is suppose to be rainbows and fairy tales. Well I worked hard suffered and dreamt about getting Read more…

A Little Something

Sometimes it is hard to get started. When you know you should make some changes in your life. Changes that will improve your health and yet it is hard to get started. Eating right and exercising sound good but are difficult to institute as your everyday lifestyle. It is easy to continue in the same patterns everyday and it is comforting to have that good old routine. Even when you know that routine is not Read more…

Groundhog Days

Covid-19 is still here. Months and months after the initial contagion we are still facing the consequences. We were originally told to lock down, put things on hold for 3 weeks then life will resume. That didn’t happen and weeks have turned into months. I’m afraid that months may turn into years. All the expert information seems suspect and now the lockdown has turned political and you are expected to pick sides. I don’t have Read more…

Playing it safe

Mitigating risks is part of the planning process. When planning for anything in life rarely do we throw caution to the wind and risk it all. A thoughtful person usually will contemplate the desired outcome weighed against the risk associated with the path towards the desired goal. Insurance is the hedge against the risk. You buy homeowners or car insurance not because you think your house will likely burn down someday or your car will Read more…

Lessons From the Pandemic

Months of enduring the lockdown should give us some instruction on what differences our future holds. 80% of the economy was deemed non-essential. That is shocking and if you work or own a business in a non-essential field you should be concerned. Without a vaccine the economic recovery will be long and hard, in some estimates 8-9 years long. The stock market has already built in a vaccine by 2020. If that occurs then the Read more…